Jacob Smith combines an unusual background of biochemistry, EMT training, and MBA education that informs his science- and patient-grounded investing approach at 11.2 Capital, where he focuses on early-stage companies solving the biggest challenges in healthcare, biology, and sustainability. His career path from Midwest growth fund to national accelerator to launching a healthcare fund before joining a San Francisco deep-tech firm represents a differentiated trajectory compared to most Bay Area VCs who start and stay within coastal firms. Jacob Smith combines an unusual background of biochemistry, EMT training, and MBA education that informs his science- and patient-grounded investing approach at 11.2 Capital, where he focuses on early-stage companies solving the biggest challenges in healthcare, biology, and sustainability. His career path from Midwest growth fund to national accelerator to launching a healthcare fund before joining a San Francisco deep-tech firm represents a differentiated trajectory compared to most Bay Area VCs who start and stay within coastal firms.