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Investor profile

Marc Andrusko

Partner, Andreessen Horowitz

About

Marc Andrusko is a partner at Andreessen Horowitz who specializes in AI-native workflows for highly regulated, transaction-heavy domains, sitting at the intersection of B2B AI applications and fintech with a focus on capital markets, payments infrastructure, and fintech crossovers into verticals like healthcare. He brings unusual operator experience from leading Plaid's personal financial management vertical and being a founding member of Marcus by Goldman Sachs' corporate development team, and is known for his thesis that 2026 will mark the death of the prompt box as AI becomes invisibly embedded in workflows rather than requiring chat interfaces. Marc Andrusko is a partner at Andreessen Horowitz who specializes in AI-native workflows for highly regulated, transaction-heavy domains, sitting at the intersection of B2B AI applications and fintech with a focus on capital markets, payments infrastructure, and fintech crossovers into verticals like healthcare. He brings unusual operator experience from leading Plaid's personal financial management vertical and being a founding member of Marcus by Goldman Sachs' corporate development team, and is known for his thesis that 2026 will mark the death of the prompt box as AI becomes invisibly embedded in workflows rather than requiring chat interfaces.

Works at

Investment focus

Stages
Seed
Series A
Series B+
Sectors
AI
Defense
BioTech
Consumer
Web3
Crypto

Investment details

Avg check size$500K - $100M
Can lead rounds
Yes
Geographies
Asia-Pacific
USA