Maria Cirino photo
Investor profile

Maria Cirino

Founding Managing Partner, .406 Ventures Fund

About

Maria Cirino is a serial founder-operator who scaled i-Cube from ~$5M to a $50M run rate through an IPO, then co-founded security company Guardent and sold it to VeriSign for ~$142M, giving her unusually deep credibility with technical founders compared to most VCs. At .406 Ventures, she focuses on enterprise IT, security, infrastructure, and digital health investments, bringing an operational mindset and apprenticeship model to help founders position and sell deeply technical products that are difficult for generalist VCs to underwrite. Maria Cirino is a serial founder-operator who scaled i-Cube from ~$5M to a $50M run rate through an IPO, then co-founded security company Guardent and sold it to VeriSign for ~$142M, giving her unusually deep credibility with technical founders compared to most VCs. At .406 Ventures, she focuses on enterprise IT, security, infrastructure, and digital health investments, bringing an operational mindset and apprenticeship model to help founders position and sell deeply technical products that are difficult for generalist VCs to underwrite.

Works at

Investment focus

Stages
Seed
Series A
Series B+
Sectors
Health
Cybersecurity
Data
AI
Enterprise

Investment details

Avg check size$2M - $5M
Can lead rounds
Yes
Geographies
USA