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Updated: March 2, 2026

Mona El Isa (Avantgarde Finance)
CEO & Founder at Avantgarde Finance | Founder of DeFi protocol Enzyme
Total Investments
3
About the Program
Program Type
Investment Focus Areas
Description
Mona El Isa is a prominent figure in decentralized finance, serving as CEO and founder of Avantgarde Finance, a DeFi native asset management, advisory, and research firm. She is also recognized as the co-founder of Enzyme (formerly Melon Protocol), a leading on-chain asset management protocol. With a background in traditional finance as a former Vice President at Goldman Sachs, El Isa has been actively involved in blockchain-based venture capital since 2016, with investments in companies such as DeversiFi, Vega, and Unslashed.