
Upfront Ventures
Founded 1996 · Santa Monica, USA
Upfront Ventures is the venture capital firm focusing on early-stage technology companies.
Need an MVP before applying?
Turn your startup idea into a working web app using AI. No coding required.
Total investments
394
Successful exits
77
About the program
Upfront Ventures is LA’s original venture firm, backing breakout companies at the earliest stages. With $2B+ AUM and over 25 years of investing, we lead early rounds in healthtech, biotech, and beyond—supporting founders from first check through scale.
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Program details
I started my career as a clinician because I wanted to help people heal — and I bring that same lens to investing. I’ve led clinical strategy at scaling startups, built partnerships across payers and providers, and lived the complexity of care delivery from the inside. I back founders building what should already exist — and roll up my sleeves to help them do it.
Investment offer
Avg Check: $750K - $7M ·
We invest in healthtech, biotech, life sciences, digital health, diagnostics, therapeutics, care delivery, value-based care, healthcare SaaS, mental health, women’s health, aging, AI/ML in healthcare, and regulated healthcare services.