Sven H. Borho is a founding partner at OrbiMed who heads the firm's public equity team and serves as portfolio manager for flagship listed healthcare strategies, including the London-listed Worldwide Healthcare Trust, giving him an unusual role that spans both specialist healthcare investing and public trust management. He emphasizes a science-first investment philosophy where understanding underlying biology and clinical science takes priority over financial metrics, distinguishing his approach from more traditional public equity managers. Sven H. Borho is a founding partner at OrbiMed who heads the firm's public equity team and serves as portfolio manager for flagship listed healthcare strategies, including the London-listed Worldwide Healthcare Trust, giving him an unusual role that spans both specialist healthcare investing and public trust management. He emphasizes a science-first investment philosophy where understanding underlying biology and clinical science takes priority over financial metrics, distinguishing his approach from more traditional public equity managers.