Updated: June 13, 2026
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Venture Capital Firm
Investment Fund
Media
SaaS

Upfront Ventures

Founded 1996 · Santa Monica, USA

Upfront Ventures is the venture capital firm focusing on early-stage technology companies.

Founder interest on IncubatorList

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Profile views (30d)

55

Founder favorites

11

Total investments

394

Successful exits

77

About the program

Description

Upfront Ventures is LA’s original venture firm, backing breakout companies at the earliest stages. With $2B+ AUM and over 25 years of investing, we lead early rounds in healthtech, biotech, and beyond—supporting founders from first check through scale.

Founded1996

Location

Program details

Value add

I started my career as a clinician because I wanted to help people heal — and I bring that same lens to investing. I’ve led clinical strategy at scaling startups, built partnerships across payers and providers, and lived the complexity of care delivery from the inside. I back founders building what should already exist — and roll up my sleeves to help them do it.

Investment offer

Check size$1,000,000 – $8,000,000
Can lead rounds
Yes
Lead preference
Always
Offer$2M - $5M
Details

Avg Check: $750K - $7M ·

Funding requirements

We invest in healthtech, biotech, life sciences, digital health, diagnostics, therapeutics, care delivery, value-based care, healthcare SaaS, mental health, women’s health, aging, AI/ML in healthcare, and regulated healthcare services.

Numbers

Total Investments
394
Total Exits
77