IncubatorListincubator listIncubatorList
DirectoryNewsletterResources
Sign InUnlock Pro AccessVC Signup

    Best Venture Capital Firms in San Mateo (2026)

    Browse updated 2026 startup programs, accelerators, incubators, and venture capital investors in San Mateo. Find open deadlines, offers, and funding.

    Updated Jun 2026

    Filters

    Refine your search

    Search
    Sort by
    Filter

    39 VCs found

    Sierra Ventures logo
    Venture Capital Firm

    Sierra Ventures

    Sierra Ventures is an early-stage venture firm investing globally with a focus on next generation enterprise and emerging technologies. We invest in the future…

    OpenCan lead
    Sierra Ventures: Sierra Ventures is an early-stage venture firm investing globally with a focus on next generation enterprise and emerging technologies. We invest in the future…. Stage: Seed, Series B +2. Focus: Enterprise, SaaS +40. Check size: $1,000,000 – $6,000,000. Venture Capital Firm, Investment Fund. Located in San Mateo, USA, North America, Asia, MENA, Europe, Oceania.
    San Mateo
    USA
    +5
    Stage

    Seed, Series B +2

    Focus

    Enterprise, SaaS +40

    Check size

    $1,000,000 – $6,000,000

    View VC Details
    Draper Associates logo
    Venture Capital Firm

    Draper Associates

    Draper Associates founded in 1985 is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a gre…

    OpenCan lead
    Draper Associates: Draper Associates founded in 1985 is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a gre…. Stage: Seed, Series B +1. Focus: Web3, Crypto +44. Check size: $100 – $1,000,000. Venture Capital Firm. Located in San Mateo, USA, North America, Europe, Asia, MENA, South America, Oceania, Africa.
    San Mateo
    USA
    +7
    Stage

    Seed, Series B +1

    Focus

    Web3, Crypto +44

    Check size

    $100 – $1,000,000

    View VC Details
    Learn Capital logo
    Venture Capital Firm

    Learn Capital

    LearnCapital is a venture capital firm focused exclusively on funding entrepreneurs with a vision for better and smarter learning. Andela is advancing human pot…

    OpenCan lead
    Learn Capital: LearnCapital is a venture capital firm focused exclusively on funding entrepreneurs with a vision for better and smarter learning. Andela is advancing human pot…. Stage: Seed, Series B +4. Focus: Education, Future Of Work +5. Check size: From $15,000,000. Venture Capital Firm. Located in San Mateo, USA, North America, Europe, Africa, Asia, MENA.
    San Mateo
    USA
    +5
    Stage

    Seed, Series B +4

    Focus

    Education, Future Of Work +5

    Check size

    From $15,000,000

    View VC Details
    Boost VC logo
    Venture Capital Firm

    Boost VC

    The #1 Virtual Reality and #1 Blockchain accelerator

    OpenCan lead
    Boost VC: The #1 Virtual Reality and #1 Blockchain accelerator. Stage: Seed. Focus: Deeptech, Hardware +3. Venture Capital Firm, Accelerator. Located in San Mateo, USA, North America, Europe, Oceania, Asia, Africa, South America.
    San Mateo
    USA
    +6
    Stage

    Seed

    Focus

    Deeptech, Hardware +3

    View VC Details
    defy.vc logo
    Investment Fund

    defy.vc

    Welcome to defy.

    OpenCan lead
    defy.vc: Welcome to defy.. Stage: Pre-Seed, Seed +1. Focus: SaaS, Enterprise +1. Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Pre-Seed, Seed +1

    Focus

    SaaS, Enterprise +1

    View VC Details
    Mohr Davidow Ventures logo
    Investment Fund

    Mohr Davidow Ventures

    Mohr Davidow invested in early-stage technology-based startups to create large new markets.

    OpenCan lead
    Mohr Davidow Ventures: Mohr Davidow invested in early-stage technology-based startups to create large new markets.. Stage: Series B, Series A +7. Focus: Enterprise Software, Health +26. Investment Fund, Venture Capital Firm. Located in San Mateo, USA, North America, Europe, MENA.
    San Mateo
    USA
    +3
    Stage

    Series B, Series A +7

    Focus

    Enterprise Software, Health +26

    View VC Details
    Emergence Capital logo
    Investment Fund

    Emergence Capital

    We bend the odds on the journey from emerging to iconic

    OpenCan lead
    Emergence Capital: We bend the odds on the journey from emerging to iconic. Stage: Seed, Pre-Seed +6. Focus: Software, Internet +15. Investment Fund, Venture Capital Firm. Located in San Mateo, Nigeria, USA, Africa, North America.
    San Mateo
    Nigeria
    +3
    Stage

    Seed, Pre-Seed +6

    Focus

    Software, Internet +15

    View VC Details
    DNX Ventures logo
    Venture Capital Firm

    DNX Ventures

    DNX Ventures is an early stage VC firm focusing on B2B Startups that are shaping industries and transforming the way we live and work.

    Open
    DNX Ventures: DNX Ventures is an early stage VC firm focusing on B2B Startups that are shaping industries and transforming the way we live and work.. Stage: Series A, Seed +3. Focus: Enterprise Software, Marketing +25. Venture Capital Firm, Investment Fund. Located in San Mateo, USA, Asia, North America, Europe, MENA.
    San Mateo
    USA
    +4
    Stage

    Series A, Seed +3

    Focus

    Enterprise Software, Marketing +25

    View VC Details
    Learn logo
    Investment Fund

    Learn

    Andela is advancing human potential by solving the global talent shortage.

    Open
    Learn: Andela is advancing human potential by solving the global talent shortage.. Stage: Seed, Pre-Seed +4. Focus: Finance, Crypto +5. Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Pre-Seed +4

    Focus

    Finance, Crypto +5

    View VC Details
    Emergence logo
    Venture Capital Firm

    Emergence

    Emergence is a venture capital firm, investing in early and growth-stage cloud and SaaS visionaries that change the way the world works.

    OpenCan lead
    Emergence: Emergence is a venture capital firm, investing in early and growth-stage cloud and SaaS visionaries that change the way the world works.. Stage: Series B, Series A +6. Focus: Enterprise Software, Marketing +29. Venture Capital Firm. Located in San Mateo, USA, North America, South America, MENA, Europe, Asia.
    San Mateo
    USA
    +5
    Stage

    Series B, Series A +6

    Focus

    Enterprise Software, Marketing +29

    View VC Details
    Sanderling Ventures logo
    Venture Capital Firm

    Sanderling Ventures

    Sanderling has supported over 90 biomedical companies earning consistently high rates of return on its venture investments.

    Open
    Sanderling Ventures: Sanderling has supported over 90 biomedical companies earning consistently high rates of return on its venture investments.. Stage: Seed, Debt Financing +2. Focus: Healthcare, Biotechnology +9. Venture Capital Firm, Micro VC. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Debt Financing +2

    Focus

    Healthcare, Biotechnology +9

    View VC Details
    Fall Line Capital logo
    Investment Fund

    Fall Line Capital

    Redefining investment in farmland and technology

    Open
    Fall Line Capital: Redefining investment in farmland and technology. Stage: Series A, Series C +2. Focus: Climate Impact, Food +17. Investment Fund, Venture Capital Firm, Private Equity Firm. Located in San Mateo, San Francisco, USA, North America. $1M - $5M available.
    San Mateo
    San Francisco
    +2
    Stage

    Series A, Series C +2

    Focus

    Climate Impact, Food +17

    Offer

    $1M - $5M

    View VC Details
    Seraph Group logo
    Venture Capital Firm

    Seraph Group

    Seraph Group invests and shares exclusive early-stage investment opportunities.

    Open
    Seraph Group: Seraph Group invests and shares exclusive early-stage investment opportunities.. Stage: Seed, Series A +1. Focus: Healthcare, Software +17. Venture Capital Firm, Angel Investor. Located in San Mateo, Foster City, USA, North America.
    San Mateo
    Foster City
    +2
    Stage

    Seed, Series A +1

    Focus

    Healthcare, Software +17

    View VC Details
    Inventus Capital Partners logo
    Venture Capital Firm

    Inventus Capital Partners

    25 yrs of Experience + Data Science + Leveraged Investments Inspire. Encourage. Grit.

    OpenCan lead
    Inventus Capital Partners: 25 yrs of Experience + Data Science + Leveraged Investments Inspire. Encourage. Grit.. Stage: Seed, Early Stage VC +3. Focus: Software, E Commerce +3. Venture Capital Firm. Located in San Mateo, Bangalore, San Francisco, USA, India, North America, Asia.
    San Mateo
    Bangalore
    +5
    Stage

    Seed, Early Stage VC +3

    Focus

    Software, E Commerce +3

    View VC Details
    Wildcat Venture Partners logo
    Venture Capital Firm

    Wildcat Venture Partners

    AI FOR THE HEALTH OF HUMANITY

    Open
    Wildcat Venture Partners: AI FOR THE HEALTH OF HUMANITY. Stage: Seed, Early Stage VC +5. Focus: Mobile, Apps +7. Venture Capital Firm, Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +5

    Focus

    Mobile, Apps +7

    View VC Details
    Portfolia logo
    Venture Capital Firm

    Portfolia

    Portfolia Investing Funds Designed For Women

    Open
    Portfolia: Portfolia Investing Funds Designed For Women. Stage: Pre-Seed, Seed +8. Focus: Real Estate, Proptech +68. Venture Capital Firm, Investment Fund. Located in Jackson, Menlo Park, San Mateo, USA, North America.
    Jackson
    Menlo Park
    +3
    Stage

    Pre-Seed, Seed +8

    Focus

    Real Estate, Proptech +68

    View VC Details
    Emergent Ventures logo
    Venture Capital Firm

    Emergent Ventures

    Emergent leads seed rounds in tomorrow's Enterprise AI leaders and helps founders get to their next milestones faster

    Open
    Emergent Ventures: Emergent leads seed rounds in tomorrow's Enterprise AI leaders and helps founders get to their next milestones faster. Stage: Seed, Early Stage VC +2. Focus: E Commerce, SaaS +14. Venture Capital Firm, Micro VC, Investment Fund. Located in San Francisco, San Mateo, USA, North America.
    San Francisco
    San Mateo
    +2
    Stage

    Seed, Early Stage VC +2

    Focus

    E Commerce, SaaS +14

    View VC Details
    Ballistic Ventures logo
    VC Fund

    Ballistic Ventures

    Cybersecurity-focused, operator-led firm that co-founds and incubates startups alongside world-class technologists, offering hands-on founder support from leade…

    Open
    Ballistic Ventures: Cybersecurity-focused, operator-led firm that co-founds and incubates startups alongside world-class technologists, offering hands-on founder support from leade…. Stage: Seed, Series A +1. Focus: Cybersecurity, AI +5. VC Fund, Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Series A +1

    Focus

    Cybersecurity, AI +5

    View VC Details
    Delphi Ventures logo
    VC Fund

    Delphi Ventures

    Integrated with research and building teams, the fund offers proprietary research-driven deal flow and end-to-end protocol support, investing primarily its own…

    Open
    Delphi Ventures: Integrated with research and building teams, the fund offers proprietary research-driven deal flow and end-to-end protocol support, investing primarily its own…. Stage: Seed, Series A. Focus: BioTech, MedTech +1. VC Fund, Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Series A

    Focus

    BioTech, MedTech +1

    View VC Details
    IMO Ventures logo
    Venture Capital Firm

    IMO Ventures

    IMO Ventures is a privately held venture capital and seed investing company across China and the US.

    Open
    IMO Ventures: IMO Ventures is a privately held venture capital and seed investing company across China and the US.. Stage: Seed, Early Stage VC +2. Focus: Transportation, Cycling +8. Venture Capital Firm, Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +2

    Focus

    Transportation, Cycling +8

    View VC Details
    SemperVirensVC logo
    Investment Fund

    SemperVirensVC

    Investing in technology startups reshaping the worlds of health, wealth, and work.

    Open
    SemperVirensVC: Investing in technology startups reshaping the worlds of health, wealth, and work.. Stage: Seed, Pre-Seed +1. Focus: Health, Finance +4. Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Pre-Seed +1

    Focus

    Health, Finance +4

    View VC Details
    Unanimous Capital logo
    Investment Fund

    Unanimous Capital

    We Invest in courageous founders.

    Open
    Unanimous Capital: We Invest in courageous founders.. Stage: Seed, Series A +1. Focus: Finance, Crypto. Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Series A +1

    Focus

    Finance, Crypto

    View VC Details
    Draper Dragon Fund logo
    Venture Capital Firm

    Draper Dragon Fund

    Draper Dragon

    OpenCan lead
    Draper Dragon Fund: Draper Dragon. Stage: Seed, Early Stage VC +1. Focus: Blockchain, Crypto +11. Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +1

    Focus

    Blockchain, Crypto +11

    View VC Details
    tidemark logo
    Investment Fund

    tidemark

    We are a growth equity firm purpose-built to help companies win and scale.

    Open
    tidemark: We are a growth equity firm purpose-built to help companies win and scale.. Stage: Series B, Series C +1. Focus: Software, Internet +2. Investment Fund. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Series B, Series C +1

    Focus

    Software, Internet +2

    View VC Details
    Moai Capital logo
    Investment Fund

    Moai Capital

    Seed Capital for Impassioned Entrepreneurs

    Open
    Moai Capital: Seed Capital for Impassioned Entrepreneurs. Stage: Seed, Pre-Seed +1. Focus: Software, Internet +3. Investment Fund, Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Pre-Seed +1

    Focus

    Software, Internet +3

    View VC Details
    KBW Ventures logo
    Family Office

    KBW Ventures

    KBW Ventures is an asset management firm focusing exclusively on venture capital, value creation, and growth equity.

    OpenCan lead
    KBW Ventures: KBW Ventures is an asset management firm focusing exclusively on venture capital, value creation, and growth equity.. Stage: Seed, Early Stage VC +1. Family Office. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +1

    View VC Details
    de Anda Capital logo
    Family Office

    de Anda Capital

    de Anda is a venture capital firm based in California that invests in seed and early stage ventures.

    Open
    de Anda Capital: de Anda is a venture capital firm based in California that invests in seed and early stage ventures.. Stage: Seed, Early Stage VC. Family Office. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC

    View VC Details
    Mason Ng logo
    Angel Investor

    Mason Ng

    Mason Ng - Technology and Product Leader @ Verizon Media

    OpenCan lead
    Mason Ng: Mason Ng - Technology and Product Leader @ Verizon Media. Angel Investor. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    View VC Details
    Patrick Spaulding Ryan logo
    Angel Investor

    Patrick Spaulding Ryan

    Patrick Spaulding Ryan is the Co-Founder, Fractional CFO and CLO of Always Blue Games. He previously worked at TikTok as a Lead Technical Program Manager, Secur…

    OpenCan lead
    Patrick Spaulding Ryan: Patrick Spaulding Ryan is the Co-Founder, Fractional CFO and CLO of Always Blue Games. He previously worked at TikTok as a Lead Technical Program Manager, Secur…. Stage: Seed, Early Stage VC. Angel Investor. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC

    View VC Details
    GS Futures logo
    Corporate VC

    GS Futures

    GS Futures is a VC firm that makes early-stage, strategic investments in the retail, sustainability, and energy sectors.

    OpenCan lead
    GS Futures: GS Futures is a VC firm that makes early-stage, strategic investments in the retail, sustainability, and energy sectors.. Stage: Seed, Early Stage VC +2. Focus: CleanTech, SDG +34. Check size: $100,000 – $5,000,000. Corporate VC. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +2

    Focus

    CleanTech, SDG +34

    Check size

    $100,000 – $5,000,000

    View VC Details
    JCI Ventures logo
    Corporate VC

    JCI Ventures

    JCI Ventures is the corporate venture arm of the merged Johnson Controls and Tyco International.

    Open
    JCI Ventures: JCI Ventures is the corporate venture arm of the merged Johnson Controls and Tyco International.. Stage: Seed, Early Stage VC +1. Corporate VC. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +1

    View VC Details
    Coupa Ventures logo
    Corporate VC

    Coupa Ventures

    Coupa Ventures invests in early- and growth-stage companies.

    OpenCan lead
    Coupa Ventures: Coupa Ventures invests in early- and growth-stage companies.. Stage: Seed, Early Stage VC. Corporate VC. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC

    View VC Details
    Cyber Mentor Fund logo
    Venture Capital Firm

    Cyber Mentor Fund

    We are a venture fund focused on early-stage companies.

    OpenCan lead
    Cyber Mentor Fund: We are a venture fund focused on early-stage companies.. Stage: Pre-Seed, Seed +1. Check size: $100,000 – $5,000,000. Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Pre-Seed, Seed +1

    Check size

    $100,000 – $5,000,000

    View VC Details
    FounderPartners logo
    Startup Studio

    FounderPartners

    FounderPartners is not a VC -- we invest our own money which better aligns ourselves with fellow founders. We're not an accelerator that teaches you how to rai…

    Open
    FounderPartners: FounderPartners is not a VC -- we invest our own money which better aligns ourselves with fellow founders. We're not an accelerator that teaches you how to rai…. Stage: Seed, Growth +1. Check size: $50,000 – $1,000,000. Startup Studio. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Growth +1

    Check size

    $50,000 – $1,000,000

    View VC Details
    Propel(X) logo
    Venture Capital Firm

    Propel(X)

    We are an angel investing platform dedicated to supporting innovative ventures stemming from scientific breakthroughs.

    Open
    Propel(X): We are an angel investing platform dedicated to supporting innovative ventures stemming from scientific breakthroughs.. Stage: Pre-Seed, Seed +2. Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Pre-Seed, Seed +2

    View VC Details
    Sunstone Partners logo
    Private Equity Firm

    Sunstone Partners

    OpenCan lead
    Sunstone Partners: Startup program. Stage: Early Stage VC, Growth +1. Private Equity Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Early Stage VC, Growth +1

    View VC Details
    DDF logo
    Venture Capital Firm

    DDF

    We are a Silicon Valley-based venture capital fund.

    Open
    DDF: We are a Silicon Valley-based venture capital fund.. Stage: Seed, Early Stage VC. Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC

    View VC Details
    ISX8 Ventures logo
    Angel Investor

    ISX8 Ventures

    We empower audacious founders with the capital and strategic support to realize their bold visions.

    OpenCan lead
    ISX8 Ventures: We empower audacious founders with the capital and strategic support to realize their bold visions.. Stage: Seed, Early Stage VC +1. Focus: Neural Network, Omni Channel +45. Check size: $50,000,000 – $100,000. Angel Investor. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC +1

    Focus

    Neural Network, Omni Channel +45

    Check size

    $50,000,000 – $100,000

    View VC Details
    Twenty Five Ventures logo
    Venture Capital Firm

    Twenty Five Ventures

    25V is a venture firm investing in early-stage companies transforming real estate, fintech, and the built world. With a focus on disciplined growth, they back f…

    Open
    Twenty Five Ventures: 25V is a venture firm investing in early-stage companies transforming real estate, fintech, and the built world. With a focus on disciplined growth, they back f…. Stage: Seed, Early Stage VC. Focus: women's, Latina +58. Check size: $50,000,000 – $150,000. Venture Capital Firm. Located in San Mateo, USA, North America.
    San Mateo
    USA
    +1
    Stage

    Seed, Early Stage VC

    Focus

    women's, Latina +58

    Check size

    $50,000,000 – $150,000

    View VC Details

    Ready to discover all VCs?

    Sign in to unlock our complete database of VCs, accelerators, and startup programs.

    FAQs about San Mateo

    What are the best VCs and accelerators in San Mateo for 2026?

    See the list below filtered to San Mateo. We surface top VCs, accelerators, and incubators with current offers and open cohorts for 2026.

    Which programs in San Mateo have upcoming deadlines?

    Check the “Open now” section for the soonest deadlines. Only future deadlines are highlighted; closed cohorts are excluded.

    Do programs in San Mateo accept remote startups?

    Many programs list remote availability. Filter results for remote or review program details to confirm hybrid/on-site expectations.

    What funding or equity terms should I expect in San Mateo?

    Offers vary by program. Look for the offer/terms in each card. Typical ranges span equity-free stipends to seed-size checks for a small equity share.